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Keywords: a hypoxia, hypoxic states, physiopathology, classification of hypoxias, a hyperoxia, Oxygenium, the causes of a hypoxia, an air hunger of cells, physiopathology of a hypoxia, a disadvantage of Oxygenium, oxygenous failure, pathological physiology
PHYSIOPATHOLOGY of the HYPOXIA. A hypoxia, mechanisms of development
Key concepts
- the Hypoxia (hypoxia; hypo - is lower, an armour. îxygenum - Oxygenium), an air hunger of an organism - the typical pathological process described by decrease of a strain of Oxygenium in tissues is lower than 20 mm of a hg and showing absolute or relative failure of a biological oxidation.
- the Anoxemia (hypoxaemia; hypo - is lower, an armour. oxygenum - Oxygenium, haema - a blood) - downstroke of Oxygenium in an arterial blood up to 60 mm of a hg and is lower.
- the Hypercapnia (hypercapnia; hyper - over, kapnos - a smoke) - rising of a strain of a carbon dioxide in an arterial blood is higher than 50 mm of a hg
- the Acapnia (hipocapnia; hypî - is lower, kapnos - a smoke) - dropping of a strain of a carbon dioxide in an arterial blood is lower than 40 mm of a hg
Educational elements
I. The characteristic of concept a hypoxia
- definition
- change of gas structure of a blood
- decrease of a strain of Oxygenium in a cell
- failure of a biological oxidation
II. Principles of classification of hypoxic states. Phylums of a hypoxia
- an acute and chronic hypoxia
- exogenous (hypobaric), circulate, gemicheskaja, histic, hyperoxic, blended
III. An etiology of hypoxias
- downstroke of partial pressure of Oxygenium in inhaled (alveolar) air
- infringement of an external respiration and a circulation
- infringement of respiratory function of a blood
- infringement of histic respiration
IV. Mechanisms of development of a hypoxia
- infringement of function of a respiratory center
- infringement of an external respiration
- infringement of transport of Oxygenium
- decrease of respiratory function of a blood
- downstroke of consumption of Oxygenium
V. A hypoxic hypoxia
- exogenous (hypobaric)
- respiratory
- dizreguljatornaja a hypoxia
VI. A circulate hypoxia
- stagnant
- ischemic
- the reloading form
VII. Gemicheskaja a hypoxia
- infringement of respiratory function of a blood
- decrease of amount of a haemoglobin
- infringement of properties of the haemoglobin connecting Oxygenium
VIII. A histic hypoxia
- an initial and secondary histic hypoxia
- absolute or relative failure of a biological oxidation
- infringement mitohondrialnogo and mikrosomalnogo oxidations
- interdigitation of oxidation and fosforilirovanija
- deficiency of substrata of a biological oxidation
IX. Blended forms of a hypoxia
- a role of a hypoxia in a pathogeny of various illnesses
- parameters of gas structure arterial and a venous blood at separate kinds of a hypoxia
- influence of a hyper-and an acapnia on development of a hypoxia
X. Age sensitivity of an organism to a hypoxia
- an acute and chronic hypoxia of a fetus and neonatal
- a pathogeny of an acute asphyxia of a fetus
XI. Mechanisms of kompensatorno-adaptive reactions of an organism at a hypoxia
- fastness of separate organs and tissues to an air hunger
- neurohumoral, respiratory, gemicheskie, gemodinamicheskie, histic mechanisms
XII. Mechanisms of pathological reactions of an organism at a hypoxia
- distress of a metabolism
- hypoxic damage of functions of separate organs
- convertibility of hypoxic states
- experimental models of various phylums of a hypoxia
XIII. A role of a hypoxia in development of stomatologic diseases
XIV. Pathophysiological bases of prophylaxis and therapy of hypoxic states
- elimination of the cause of a hypoxia
- oxygenous therapy
- a hyperbaric oxygenation
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Keywords: a hypoxia, hypoxic states, physiopathology, classification of hypoxias, a hyperoxia, Oxygenium, the causes of a hypoxia, an air hunger of cells, physiopathology of a hypoxia, a disadvantage of Oxygenium, oxygenous failure, pathological physiology
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