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Keywords: an allergy, allergic responses, immunodefence, an immunoglobulin, hypersensitivity, an autoallergy, an allergen, an anaphylaxis, lymphokines
PHYSIOPATHOLOGY of the ALLERGY. A general etiology and the general mechanisms of an allergy
Key concepts
- the Allergy (a sensibilization; a hypersensibility; allos, ergon - other mean of reaction; sensibilis - sensitive) - the hyperreactivity of an organism on action of alien materials, is more often with antigenic properties (allergens); the sample pathological process educing at action of antigenic irritants on an organism.
- the Allergen (allos - another, ergon - work, activity, a parentage) - alien material, capable to invoke rising sensitivity of an organism to antigenic irritants.
- Sensitized lymphocytes - lymphocytes with the increased reactive sensitivity to allergens.
- Allergic antibodies - specific immunoglobulins (IgE), responding with allergens.
- Pathoimmune mechanisms - mechanisms of interaction of allergens with physiological system of the immune answer: sensitized lymphocytes and allergic antibodies.
- the Hypersensibility of time-lapse type - interaction of an allergen with physiological system of the immune answer, adducting in formation of sensitized T lymphocytes.
- the Hypersensibility of immediate type - interaction of an allergen with physiological system of the immune answer, adducting in formation of pathogenic complexes an antigen + an antibody.
- Pathochemical mechanisms of development of an allergy - mechanisms of formation and pathogenic action on an organism of lymphokines, etc. mediators of an allergy.
- Lymphokines - the biological awake materials formed immunoagressivnymi by T lymphocytes (killers) and participating in formation of allergic responses of time-lapse type.
- Mediators of an allergy - the biological awake materials formed by various somatic cells of an organism at action of pathogenic complexes ÀÃ+ÀÒ by means of which allergic responses of immediate type are carried out.
- Pathophysiological mechanisms of an allergy - mechanisms of development of pathological reactions, processes and diseases of an allergic parentage (a bronchial asthma, a urticaria, etc.).
- the Anaphylaxis (anaphylaxia - defencelessness, ana - anatropic, inverse action, phylaxis - self-defense) - the got hypersensibility of an organism to action of alien proteic matters (an acute anaphylaxis, phenomenon Artjusa-Saharova).
Educational elements
An allergy. Definition of concept and a general characteristic
- Interaction of an allergy and immunodefence, an allergy and an inflammation
- Kinds of allergic responses, classification
An etiology of an allergy
- Exogenous and endogenic allergens; their kinds
- the Nature of the allergens invoking an imediate-type allergy
- the Nature of allergens at an allergy of time-lapse type
- the Role of conditions of an external environment in development of an allergy
- the Role of a reactivity of an organism in development of an allergy
- " Entrance hiluses " allergies
- Nervous factors of development of an allergy
- Hormonal factors of development of an allergy. A role of a thymus gland
- the Age allergy
- Value of ancestral predisposition to an allergy
- Immunogeneticheskie factors in mechanisms of development of an allergy
The general mechanisms of development of an allergy
Pathoimmune mechanisms of an allergy
- Sensitized T lymphocytes, T-cells
- Allergic antibodies, secondary B cells
- Pathochemical mechanisms of an allergy
- Mediators of allergic responses: lymphokines and biologically awake materials
Pathophysiological mechanisms of an allergy: an inflammation, a fever, a shock
The seasons (stages) of allergic responses of time-lapse type; their mechanisms of development
- Mechanisms of a sensibilization at allergic responses of time-lapse type
- Pathoimmune mechanisms of a hypersensibility of time-lapse type
- the Priming reaction of immunocompetent cells on an antigenic boring. Formation of sensitized T lymphocytes and T-cells
- the Priming reaction of immunocompetent cells on an antigenic boring. Formation immunoagressivnyh T-cytotoxic lymphocytes
Mechanisms of a sensibilization at an imediate-type allergy
- Pathoimmune mechanisms of rising of sensitivity of immediate type
- the Priming reaction of immunocompetent cells on an antigenic boring. Formation of secondary B cells and allergic antibodies
- Secondary reaction of immunocompetent cells to an antigenic boring. Formation of pathogenic pathoimmune complexes an allergen + an antibody
Pathochemical mechanisms of development of a slow-acting hypersensibility
- Mechanisms of action of lymphokines
- Pathophysiological mechanisms of a hypersensibility of time-lapse type (the basic forms): bacterial and a contact allergy
- Value of allergic responses of time-lapse type for a problem of transplantation of organs and tissues
- Principles of revealing of an allergy of time-lapse type
- Pathes of a desensitization at an allergy of time-lapse type
- the Seasons (stages) of an imediate-type allergy
- the Pathophysiological role of system of a complement in mechanisms of formation of allergic responses
- Pathochemical mechanisms of development of a hypersensibility of immediate type
- Mediators of allergic responses of immediate type, the mechanism of their action
- Pathophysiological mechanisms of a hypersensibility of immediate type (the basic forms): atopicheskie illnesses, anaphylactic reactions, cytolytic reactions and reactions of free circulating cell-bound immune complexes "ÀÃ+ÀÒ" (Central Electoral Committee)
- Mechanisms of "aboriginal" and general reactions at medicinal and a food allergy
- Pathophysiological bases of methods of revealing of an imediate-type allergy
- Kinds and mechanisms of a desensitization at an imediate-type allergy
Mediate forms of an allergy
An autoallergy. Definition
- Initial and secondary autoallergens; complex autoallergens
- the Interrelation of physiological autoimmune and pathological autoallergic reactions
- Mechanisms of restriction of immune tolerance and originating of an immune autoaggression
- Infringements of immune system as a basis of an autoallergy
- the Autoaggression of "forbidden" clone T-and B-cells
- Genetical defect T-supressorov and an autoallergy
- Vegetative mutation T-and B-lymphocytes in mechanisms of an autoallergy
- Pathophysiological mechanisms of autoallergic reactions: entsefalomielit, a thyroiditis, an orchitis, a red systemic lupus, a pseudorheumatism, a myasthenia, a rheumatic carditis, a glomerulonephritis, a ulcerative colitis
- Principles of revealing and therapy of autoimmune diseases
The immune conflict of mother and a fetus, his basic forms and consequences. An allergy neonatal. Sources of an allergization of children. Value of an allergy in a pathogeny of diathesises
A pathogeny immunopatologicheskih reactions at children. Immunodefitsitnye states at children
A role of transplacental transmission of immunoglobulins in a pathogeny perinatalnyh autoimmune and allergic diseases
Allergic diseases in stomatologic practice. A role of an allergy in a pathogeny of diseases parodonta, a mucosa of an oral cavity, sialadens. A role of professional factors in development of allergic diseases at stomatologists (for stomatfaka)
To discuss a material at a forum of a site
Keywords: an allergy, allergic responses, immunodefence, an immunoglobulin, hypersensitivity, an autoallergy, an allergen, an anaphylaxis, lymphokines
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