| |
Keywords: a clinical immunology, lecture, Zemskov, lecture on immunologies, immunocorrectors, immunity, medicines, a stimulation of immunity, principles of purpose of the preparations, immunocorrect preparations, treatment
PRINCIPLES OF PURPOSE OF IMMUNOCORRECT PREPARATIONS
Lecture on a clinical immunology of professor A.M.Zemskova
Any pathology is accompanied by frustration of immune system. Both the augmentation, and downstroke of activity of immune system - is bad. Correct diagnostics and correction of immune infringements raises efficiency of any treatment and is always useful to the patient. For correction use a special class immunotropnyh preparations.
Dolaboratornoj as an evaluation of the immune status the method of questioning can serve. To the patient set some questions. If even he answers one of them positively, it testifies to those or other infringements in immune system.
- Frequency of infections. At the person with normally functioning immune system frequency of infections no more than 4 in one year (for the child - no more than 6).
- Atypical temperature reaction at presence of an infection:
- absence of a fever (it is not observed rises in temperature);
- a unmotivated fever;
- a long subfebrile condition (37,1 °-37,3 ° Ñ) - more than 12 day.
- Lingering current of any diseases (more than 3 weeks).
- Presence at the patient of any chronic diseases.
- Presence at the patient of any intolerances and allergic reactions.
- Autoimmune diseases.
- Onkopatologija.
- Appendo-and tonzilloktomija.
- Gastro-and enteropatii, often constipations, a diarrhea.
- Phlegmons, abscesses, a paraproctitis, the tightened pustular diseases of a skin.
- Repeated limfoadenopatii.
- Long application tsitostatikov, corticosteroids, antibiotics, etc. medical products.
- Transferring to last 6 months of traumas, combustions, serious operations.
- Harmful habits.
On the basis of a questionnaire it is possible to judge 7 sets of symptoms:
- the Infectious set of symptoms- a chronic subfebrile condition, a fever of an obscure etiology, relapsing diseases mild, often ORVI, bacterial defeats of a skin, defeat of nails, relapsing conjunctivitises, a stomatitis, a caries, relapsing herpes, limfoadenity, a dysbacteriosis and a generalized infection.
- the Allergic set of symptoms- allergoporazhenija skins and mucous, dermatitises, eczemas, allergic rhinites.
- the Autoimmune set of symptoms- inflammatory processes in a locomotorium, HARD CURRENCY, a scleroderma, a glomerulonephritis, a diabetes, neurologic frustration, a sclerosis, a thyroiditis, autoimmune defeats of a liver, barreness, psychopathic diseases.
- the Climacteric set of symptoms
- the Initial immunodeficiency- at children - a set of symptoms of the Moon - Barra (frustration of gait, since in a stalemate. Process is involved a cerebellum), set of symptoms Viskotta-Oldridzha (hemorrhagic frustration), a set of symptoms di Georges.
- Limfoproliferativnyj a set of symptoms- tumours in lymphatic system, a lymphoid leukosis, sarcoma Kaposhi, a group hyperplasia of lymph nodes, a mononucleosis and often hyperadenosises.
- Secondary immunodeficiencies- all kinds of an infectious set of symptoms with torpid chronic atipicheskim current, a hyperpegmentation of a skin, AIDS.
If there is 1 set of symptoms from 7 and pathological process is localized in 1 system of organs - group of risk (exception: serious sets of symptoms).
If the combination of sets of symptoms and disease some systems of organs - group of the increased risk are found out in the patient affects. Such patients need the help immunoterapevta.
Principles of work with the patient.
- Interrogation.
- Verification of the clinical diagnosis. Immune frustration arise at infections, change of a feed, after consumption of Sodium nitritums, at loss of fiber, a peptic ulcer, after combustions, traumas, stresses, after pulmonary diseases, operations, etc. - auxiliary diagnostics.
- Work with the general analysis of a blood. Change of amount of leucocytes and lymphocytes is taken into account. Diagnosticheski the deviation from norm on 25-30 % is significant. As relative sizes are poorly informative, it is necessary to define absolute number of researched cells. At this stage application of small immunocorrectors is recommended: vitamins, beer yeast.
- the Evaluation of the immune status. It is proved, that almost always among significant parameters there are T-lymphocytes, means always it is necessary to determine their level.
- Statement of the diagnosis:
- an establishment of constant presence of an immunopathology;
- definition of vectorial changes (augmentation, downstroke) immune parameters;
- definition of character of an immunopathology (in what part of immune system a pathology);
- definition of a degree (expressiveness) of these changes.
- the Immunocorrection (immunomoduljatsija) - process of elimination of immune infringements.
- the Immunoreabititation - process of restoration of normal functioning of immune system with the help medicamental, not medicamental and other influences for convalescence of the patient or achievement of a proof remission. Distinguish specific (in clinic under observation immunoterapevta) and applied (an out-patient treatment or treatment domiciliary) immunoreabititatsiju.
Stages of an immunoreabititation:
- Clinical - 14-45 days. The patient except for basic therapy receives starting immunocorrectors.
- Out-patient - months and years. The patient carries out purposes of the doctor.
- Sanatorium-health-resort. Once a year.
To remove immune frustration it is necessary to eat correctly. First of all animal protein are necessary. Soya fiber is obviously insufficient, since is badly acquired and shapes albuminous dystrophias.
MAIN PRINCIPLES OF PURPOSE OF IMMUNOCORRECTORS
- the Immunocorrector does not replace, and supplements basic treatment of any diseases. He is a component of complex treatment.
- the Evaluation of character of immune infringements, definition of the formula of frustration of immune system.
- Definition of a degree of an immunopathology.
- Definition of dependence of an immune reactivity from groups of a blood.
- Taking into account immunotropnosti traditional medical products, knowledge of targets of an immunocorrection, conservation of profile action immunomoduljatora at the same immune infringements, even at various diseases.
- Influence of initial character of an immunopathology on efficiency of an immunocorrection.
- Taking into account of side effects of immune preparations.
An evaluation of character of immune infringements. Definition of the formula of frustration.
To reveal immune frustration, it is necessary to estimate the immune status. The immune system has 3 links - the T-part, the V-part and a nonspecific cytophagous part. It is necessary to estimate each part.
the T-part.T-lymphocytes: T-killers, T-helpery, T-supressory. Their amount either enlarged, or reduced.
An evaluation of function of the T-link: 1) intensity dermal reactions depends on intensity of intracutaneous tests; 2) RBTL.
the V-part.V-lymphocytes. An evaluation: 1) an evaluation of level IgM, IgA, IgG, IgE. 2) RBTL.
the Cytophagous part.Monocytes and macrophages. An evaluation of function of a cytophagous link:
- absorbing activity - is estimated by a cytophagous parameter and cytophagous number;
- metabolic activity - is estimated by tests NSTspont- momentary metabolic activity and NSTan active- deferred.
There are unripe cells of a 0-cell. Exist NK and EK-cells which cause protection against malignant cells.
The problem of the clinical immunologist - to estimate what part is inadequate at the given patient.
A degree of definition immune narushenpj. Not any infringement speaks about something. (PB/PZ - 1) *100 %. If rasschetnaja the size is negative - there is an immunodeficiency if it is positive - a hyperfunction. If the size of 1-33 % - 1 degree of immune infringements - is ignored. 34-66 % - 2 degree - treatment by 1 preparation. More than 66 % - a serious condition. Reception of several preparations is necessary.
The formula of frustration of immune system.
Th-3the Hardware +2IgA +2the T-part can be inert, depressirovano, supressirovano, is debalanced. In this case - supressirovano, the stimulation of the T-link hence is necessary.
Th-3- Downstroke T-helperov of 3-rd degree.
To discuss a material at a forum of a site
Keywords: a clinical immunology, lecture, Zemskov, lecture on immunologies, immunocorrectors, immunity, medicines, a stimulation of immunity, principles of purpose of the preparations, immunocorrect preparations, treatment
|
