 Keywords: a medicine, psychology, the information, not receptor action of medicinal substancesReznikov K.M.psychological and information aspects of action of medicines/Ê.Ì. Reznikov, O.JU.Shiryaev, M.K.Reznikov // Pressing questions of psychiatry, an addictology and medical psychology. Release 4.-Voronezh: Publishing house " Èíôà ", 2002.-with 152-154. PSYCHOLOGICAL AND INFORMATION ASPECTS OF ACTION OF MEDICINESFor an evaluation of true efficiency of action of a new medicinal preparation in world practice the double blind control when neither the patient, nor the doctor do not know that is applied to treatment is used: a true preparation or a placebo, having the same form, color, the size, mass and the same form-building substances, as a researched preparation, but without the working beginning which medical properties are established. It is known, that the placebo can cause a positive effect in 30-35 % of patients and in this case explain mechanisms of medical action rather inconveniently. For example, unitary application of a placebo (intravenous introduction of an isotonic solution of a sodium of Sodium chloridum) for patients with an alcoholic abstinent set of symptoms appeared more effective, than compared preparations (tiroliberin, a thyrotropin - rilizing Hormonum), in decrease of physical delicacy and thirst while specified Hormonums were more authentically effective concerning other signs, such, as an inclination to alcohol, irritability, bad mood, infringements of dream (A.I.Belkin, O.JU.Shiryaev, 1987). Even more convincing data on positive placebo - effect result A.L. Hamburg with co-authors, (1978). They specify a high positive effect of placebo - therapy of patients with an alcoholizm, expressed in normalization of dream and appetite, decrease of irritability, putting off of the phenomena of an abstinence. These examples testify that our knowledge of formation of medical effects of preparations are still far from perfect also a problem of placebos - effects consists not only in existence of psychological aspect of a pharmacotherapy, but also, obviously, in any other mechanisms of action on an organism of medicinal substances. Psychological aspects in operation medical products are investigated well enough and practically all of them are connected to influence of a preparation on an organism before his introduction. The smart advertising which is holding back about by-effects of preparations, advice of relatives and neighbours with success using this or that agent, the accessible medical and pharmaceutical literature from which it is possible to get knowledge of medicines - an external background forming the attitude of the patient to medicines. More thin psychological aspects of the attitude to medicines are shaped imperceptibly and unostentatiously. In this respect the important role is played with the price of a preparation. In many cases the it is higher, the it is more to it trust and an opportunity of optimum effect sharply grows. The sufficient psychological factor is the source of reception of medicines: As a rule, it is considered to be, that preparations of a natural parentage are less dangerous and more effective, that not always corresponds to the validity, and at times results in an aggravation of symptoms of patients. The size of the medicinal form, for example, tablets, also plays the psychological role: large tablets render more appreciable action, and fine on the contrary. At the same time purpose of the big tablets on the size can cause alarm of the patient since he can count, that small tablets any more do not operate also his affairs bad. This concerns and to amount of purposes. In I.P.Lapina's opinion (1990) color of an accepted medicine is a significant information element among psychological factors of a pharmacotherapy as the certain expectations of his action are connected to color of a preparation. In A.V.Rubitelja's researches with co-authors (1987), Buchulew L.W., K.E. Cojfield (1982) it is shown, that expectation is connected to white color basically of abirritating action; red, yellow and green colors cause expectation basically of excitant, tonic and stimulating action; violet - rising of mood, brown color appeared more preferably for hypnagogues, etc. In this plan the certain role color and veneering of packing can play. Even the name of a preparation frames certain adjust the patient and the degree of novelty of the name affects effect. Frequently it is possible to hear, that Seduxenum is more effective, than Relanium or Sibazonum, only because the first name earlier, more known, than the others though it is the same preparation. All these data testify that psychological adjust the patient, determined by many factors, at times plays a main role in treatment and undoubtedly it should be taken into account by medical workers. However, the well-known phenomenon of long-range action of medicines when the preparation changes this or that parameter of an organism, being near to it, thus it can be an isolated organ as, for example, in N.P.Kravkova's experiences (1927) rabbits isolated an ear, or testing by method Follja of compatibility of a medicine and the patient, widely used now, testify to presence of others, than psychological, mechanisms of interaction of molecules of medicinal substance with tissues of an alive organism. Possible ways of such interaction are submitted in a drawing.  Information processes arising at penetration of medicinal substance into an organism can be distributed on 4 streams which finally result in change of a metabolism and function of a living cell. The standard receptor mechanism of formation of pharmacological effect is not the only thing. The moving molecule of medicinal substance is accompanied by an electromagnetic field which characteristics reflect its properties. This field cooperates by the resonant phenomena with an electromagnetic field of molecules of an organism changing functional - metabolic processes in a cell. The third way of transfer of the medicinal information is realized by means of the hydrated environment of a molecule of the medicinal substance cooperating with chains klasterov of structured water of an organism therefore process of proton transfer of the information on bioframes of cells of an organism (K.M.Reznikov changes. 1999). As the unity of substance and consciousness (V.N is hypothetically shown. Tkachuk with co-authors, 2001) quite pertinently to admit indissoluble connection of changes of psychological processes with changes of structural - metabolic processes during formation of pharmacological effect. This indissoluble connection determines both process of disease, and process of convalescence, and a state of health. the List of the literature
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